The Secret to Radiant, Youthful Skin

Exotokine is a professional-grade, plant-based formulation developed to deliver intensive hydration, restore the skin barrier, and promote visible skin revitalization. Created specifically for in-clinic use, it supports post-treatment recovery and long-term skin health.

What is Exotokine?

Exotokine is derived from the scientific fusion of Exo (extracellular vesicles/exosomes) and tokine (cytokines, anti-inflammatory immune proteins). Developed through stem cell research at Soongsil University in Korea since 2018, Exotokine is manufactured using a proprietary EV membrane filtration system to isolate and purify active extracellular vesicles.

Its core ingredient is 100% plant-derived, utilizing Centella Asiatica–extracted EVs (exosomes) and enriched with multiple EGF growth factors to optimize skin regeneration and barrier integrity within clinical aesthetic protocols.

Clinically Active Ingredients

– Stem Cell Extract
– 0.1% Concentrated Centella Asiatica Extracellular Vesicles (PP Exosome)
– NMN (Nicotinamide Mononucleotide)
– Niacinamide
– 9 Active Epidermal Growth Factors (EGFs)
– Madecassoside

Benefits of Exotokine

1. Radiance and Youthful Appearance

Restores a natural glow and reduces visible signs of aging.

2. Moisture
Improvement

Long-lasting hydration to combat dryness.

3. Wrinkle
Reduction

Minimizes fine lines and improves skin elasticity.

4. Barrier
Restoration

Strengthens the skin’s protective layer, preventing environmental damage

5. Even
Texture

Creates a smoother and more uniform skin surface.

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What is the Exosome Complex?

The exosome complex (also referred to as the PM/SCI complex) is a multi-protein intracellular structure responsible for degrading various types of RNA molecules. It plays a critical role in RNA processing and turnover, ensuring cellular homeostasis.

Exosome complexes are present in both eukaryotic cells and archaea. In bacteria, a simpler but functionally similar system called the degradosome performs equivalent RNA-degradation tasks.

What are Cytokines?

Cytokines are small protein molecules (5–25 kDa) that function as key mediators in cell signaling. Although they cannot penetrate the lipid bilayer of cells, they act as immunomodulators through autocrine, paracrine, and endocrine pathways. Cytokines regulate immune responses, inflammation, and cell communication. While they share some similarities with hormones, their classification remains an area of ongoing scientific investigation.

Membrane Exosome Filtration created by Bae Lab

PP Exosomes by BAE Lab

PP Exosome is a 0.1% pure, plant-derived exosome developed through BAE Lab’s proprietary PP-EXO™ technology. By synergistically combining exosomes extracted from medicinal plants with high-performance active ingredients, BAE Lab has created the Exotokine skin booster—a scientifically advanced solution designed for clinical results.

Committed to transparency, BAE Lab openly shares its complete exosome extraction and filtration process, offering both doctors and end-users full visibility into the formulation and ingredient integrity.

Why BAE Lab? A Research-Driven Approach

BAE Lab is a research institution under Soongsil University in Korea, specializing in academic-level exosome studies. Every active ingredient and formulation is independently validated before entering production, ensuring scientific rigor at every stage.

BAE Lab oversees the entire development cycle—from exosome research and membrane-based filtration to final packaging—maintaining strict quality control throughout.

What Sets BAE Lab Apart:

One of the few labs globally to transparently disclose its exosome filtration methodology
Academic-driven R&D before mass production
Focused on developing exosomes that deliver measurable, functional results on real skin

Our Mission:
To create the most effective, clinically functional exosomes for professional skincare applications.

Versatile Applications

Exotokine Skin Regenerator is formulated for flexible use in clinical practice. It can be applied topically or delivered through microneedling (MTS), fitting naturally into protocols focused on tissue repair, skin renewal, and recovery after aesthetic procedures. Its biologically active profile supports cellular communication and regeneration, making it a strong addition to advanced medical aesthetic treatments.

Clinical Use Cases:

Microneedling (MTS)
Post-laser and energy-based treatment recovery
Mesotherapy
Post-acne skin repair
Ongoing anti-aging protocols

Reduce dull tone, fine lines, and visible skin stress. Support skin regeneration with precision-driven science and clinically guided cellular signaling.

Clinical Relevance

Exotokine is supported by extensive clinical research in the fields of cosmetic dermatology and aesthetic medicine. Its targeted formulation is designed to assist with:

Clinics and practitioners integrate Exotokine into advanced protocols to accelerate recovery, enhance treatment outcomes, and support long-term skin regeneration.

Developed by Professor Won-Gyu Bae

Exotokine was developed by Professor Won-Gyu Bae, a leading bioengineering researcher from Soongsil University, Korea. With advanced academic training from Stanford University and Seoul National University, Professor Bae brings a unique blend of innovation, clinical insight, and scientific precision to the field of aesthetic medicine.

Professor Bae’s Vision:
“To develop next-generation skincare and medical solutions rooted in biomimicry and breakthrough regenerative science.”